Speaker
Dr
Maria Marcaida
(EPFL)
Description
During this seminar, two experimental structural biology projects will be discussed illustrating current challenges and limitations in the field. The first will show how sequence identity may fail in predicting the protein structure and function. The second deals with investigating protein-protein interactions experimentally with the aim of creating small molecule inhibitors that block such interaction. Our results from biophysical experiments (CD and ITC) as well as NMR will be presented and discussed.
Submitting to: | Integrative Computational Biology workshop |
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Primary authors
Ms
Anastasia Theodoropoulou
(EPFL)
Prof.
Didier Trono
(EPFL)
Prof.
Giovanni D'Angelo
(EPFL)
Dr
Laia Simo
(EPFL)
Dr
Luciano Abriata
(EPFL)
Dr
Maria Marcaida
(EPFL)
Prof.
Matteo Dal Peraro
(EPFL)