Speaker
Joseph Zaccai
Description
Following a period of strong development of the contrast variation method using H2O/D2O exchange on physical-chemical and readily available soluble protein samples,D11 hosted a number of challenging experiments in biology—in particular on protein-nucleic acid interactions. Important results were obtained on the inner structures of plant viruses, ribosomes and chromatin. A study of aminoacyl-tRNA synthetases interactions with their tRNA substrates established in-beam structural biochemistry on D11.