Mar 14 – 17, 2023
Europe/Paris timezone

Session

Clip Session

Mar 14, 2023, 4:30 PM

Presentation materials

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Heitor Gobbi Sebinelli (Laboratory of Membrane Proteins and Membrane Systems, Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif sur Yvette, France), Christine Jaxel (Laboratory of Membrane Proteins and Membrane Systems, Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif sur Yvette, France)
Poster

Ist2 is a yeast transmembrane protein localized in the endoplasmic reticulum (ER). It is a structural homolog of TMEM16 proteins, a family of transporters described as scramblases, i.e., proteins that catalyze facilitated diffusion of lipids in a non-specific manner, and/or anion channels.
Ist2 is made of a N-terminal transmembrane domain, as well as a long cytosolic C-terminus that binds to...