Poxviruses are large enveloped dsDNA viruses that infect a wide range of eukaryotes and can spread in human populations. Vaccinia virus (VACV) is the type species of the Poxviridae family and serves as a well-established laboratory model to study virus-host interactions. Notably, the complex infectious particles of VACV are enveloped and brick-shaped. On the inside, there are two lateral...
Nienke Buddelmeijer
Institut Pasteur, Université de Paris, CNRS UMR6047, INSERM U1306, Unité Biologie et Génétique de la Paroi Bactérienne, 25-28 rue du docteur Roux, 75724 Paris cedex 15
The post-translational modification of bacterial lipoproteins is catalyzed by a sequential action of three integral membrane enzymes. Lgt transfers a diacylglyceryl moiety from phospholipid...